- https://efsa.onlinelibrary.wiley.com/doi/pdf/10.2903/j.efsa.2009.1236
- https://pubmed.ncbi.nlm.nih.gov/28809383/
- https://pubmed.ncbi.nlm.nih.gov/33619835/
- https://pubmed.ncbi.nlm.nih.gov/26133538/
- https://www.sciencedirect.com/science/article/pii/S2772572322001844#:~:text=Conclusion,production%20in%20the%20model%20colon.
The Verdict
The enzymes lactase and alpha-galactosidase found in FODZYME could potentially help with symptoms of lactose intolerance and IBS following ingestion of lactose and other FODMAPs.
Reviews are for informational purposes only and do not constitute medical advice
Claims
The world's first enzyme blend that targets FODMAPs directly
Breaks down triggers in the stomach, before they can reach or affect the bowels
Breaks down fructans, GOS and lactose that can trigger gut symptoms like abdominal pain, excessive gas, bloating, constipation, and diarrhoea
The Research
Lactase is clinically proven to aid lactose digestion. The Europeans Food Safety Authority recommend a dose of 4500 FCC units of lactase with each lactose containing meal. FODZYME confirmed that a single serving of FODZYME meets these requirements.
Alpha-galactosidase shows mixed results for treating symptoms of irritable bowel syndrome (IBS) in clinical trials. However, alpha-galactosidase has been shown to help prevent an increase in symptoms following ingestion of foods specifically high in galacto-oligosaccharides (e.g. legumes) in people with IBS at a dose of 150-300 GALU. FODZYME confirmed that a single serving meets these requirements.
To our knowledge, fructan hydrolase has not yet been studied in human clinical trials.
A lab-based study in a simulated gut model found that FODZYME was able to break down 90% of fructan-type inulin within 30 minutes. However, no human clinical trials of FODZYME have yet been published, to our knowledge.
What's in it?
Enzyme blend: Fructan Hydrolase, Lactase, Alpha-Galactosidase (serving size 750mg).
Other ingredients: Dextrin
*price based on Home Kit and one serving per day
Read the research
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