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Price: £49.99 per month
Date reviewed: 10/2023
- Digestive Health
- Gut Barrier Integrity
- Gut Immune Function
- Cardiovascular Health
- Dermatological Health
- Micronutrient Synthesis
What's in it?
37 billion AFU (Bifidobacterium longum SD-BB536-JP, Bifidobacterium breve SD-BR3-IT, Lactiplantibacillus plantarum SD-LP1-IT, Lacticaseibacillus rhamnosus SD-LR6-IT, Lacticaseibacillus rhamnosus HRVD113-US, Bifidobacterium infantis SD-M63-JP, Bifidobacterium lactis SD-BS5-IT, Bifidobacterium lactis HRVD524-US, Lactobacillus crispatus SD-LCR01-IT, Lacticaseibacillus casei HRVD300-US, Bifidobacterium breve HRVD521-US, Bifidobacterium longum HRVD90b-US, Bifidobacterium lactis SD150-BE, Limosilactobacillus fermentum SD-LF8-IT, Lacticaseibacillus rhamnosus SD-GG-BE, Limosilactobacillus reuteri RD830-FR). 3.3 billion AFU (Bifidobacterium lactis SD-CECT8145-SP, Bifidobacterium longum SD-CECT7347-SP, Lacticaseibacillus casei SD-CECT9104-SP, Ligilactobacillus salivarius SD-LS1-IT, Bifidobacterium breve SD-BR3-IT). 5.25 billion (Lactiplantibacillus plantarum SD-LPLDL-UK, Bifidobacterium lactis SD-MB2409-IT). 8.05 billion AFU (Bifidobacterium adolescentis SD-BA5-IT, Limosilactobacillus reuteri SD-LRE2-IT). 400mg Indian Pomegranate [whole fruit] (Punica granatum) (>40% Polyphenolic + Phenolic Bioactives). Other ingredients: Acid-Resistant Vegan Outer [chlorophyllin] and Inner Capsules [hypromellose, fermented gellan gum, water], Organic rice fiber, Organic rice extract blend.
What does the research say?
Some of the individual strains in Seed DS-01 have been studied in clinical trials for digestive health (constipation), dermatological health (atopic dermatitis) and cardiovascular health (cholesterol), but this product and it’s specific combination of bacteria has not been studied clinically.
According to their website, there are two ongoing clinical studies in people with irritable bowel syndrome (IBS) and in people following antibiotic therapy. However, results are not yet available.
Some of the strains in this product have only been shown to have benefits in animal or lab-based studies, but not in human clinical trials. Also, it is not clear on the dose of each individual strain in this product. Therefore, we cannot confirm whether the levels of individual strains in this product are sufficient when compared to randomized, controlled trials.
Pomegranate polyphenols have been shown to have a prebiotic effect although the dose in one daily capsule of DS-01 (~160 mg) may be too low to have any prebiotic effects when compared to clinical trials (300-1000mg).
An independent, unpublished study with SHIME (Simulator of Human Intestinal Microbial Ecosystem) found that around 100% of the bacteria in Seed DS-01 reach the colon alive. However, this is an in vitro (lab-based) model.
DS-01 contains individual strains that may be helpful for some aspects of digestive, dermatological, and cardiovascular health. However, the combination of probiotics at these doses found in DS-01 needs to first be investigated clinically before claims can be supported.
Reviews are for informational purposes only and do not constitute medical advice